The number of children diagnosed with challenging behaviors associated with neuropsychiatric diagnoses is on the rise. As such, offices where children are frequently seen for treatment and services need to be prepared for addressing these challenging behaviors.  Physicians’ offices, in particular, will benefit from preparedness planning, training, and management of behavioral outbursts in an office setting to reduce risk and increase treatment outcomes. In this Clinical Connections Presentation, our interdisciplinary care team will review proven strategies related to assessing and reducing challenging behaviors of neurodiverse patients in a primary care office setting. This presentation is designed for all members in a primary care setting including physicians, nurses, medical assistants, and front office staff.